Search on: RECEPTORS, TIE 
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Descriptor English:   Receptors, TIE 
Descriptor Spanish:   Receptores TIE 
Descriptor Portuguese:   Receptores de TIE 
Synonyms English:   TIE Receptor Tyrosine Kinases  
Tree Number:   D08.811.913.696.620.682.725.400.925
D12.776.543.750.060.687
Definition English:   A family of structurally-related tyrosine kinase receptors that are expressed predominantly in ENDOTHELIAL CELLS and are essential for development of BLOOD VESSELS (NEOVASCULARIZATION, PHYSIOLOGIC). The name derives from the fact that they are tyrosine kinases that contain Ig and EGF domains. 
Indexing Annotation English:   GEN; prefer specifics
History Note English:   2004; use RECEPTORS, TIE (NM) 1999-2003 
Allowable Qualifiers English:  
AD administration & dosage AE adverse effects
AG agonists AN analysis
AI antagonists & inhibitors BI biosynthesis
BL blood CF cerebrospinal fluid
CS chemical synthesis CH chemistry
CL classification CT contraindications
DF deficiency DU diagnostic use
DE drug effects EC economics
GE genetics HI history
IM immunology IP isolation & purification
ME metabolism PK pharmacokinetics
PD pharmacology PH physiology
PO poisoning RE radiation effects
SE secretion ST standards
SD supply & distribution TU therapeutic use
TO toxicity UL ultrastructure
UR urine  
Record Number:   38227 
Unique Identifier:   D042764 

Occurrence in VHL:
 

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